Assistant Professor in the field of Physics

Dr. Nihar Ranjan Jena received his PhD degree from Banaras Hindu University (BHU), India in 2006. Subsequently, he did his Postdoctoral from the Hebrew University of Jerusalem, Jerusalem, Israel, and National Taiwan Normal University, Taipei, Taiwan. He has also worked as a Guest Scientist in the German Cancer Research Center (DKFZ), Heidelberg, Germany, and a research scientist in the Molecular Biophysics Unit, Indian Institute of Science, Bangalore, India. He is also a recipient of the Indo-Australia visiting fellowship (2013-2014) from the Indian National Science Academy, which was availed in the University of Queensland, Australia. Currently, he is working as an Assistant Professor in Physics at the PDPM-Indian Institute of Information Technology Design and Manufacturing Jabalpur, India.

Artificial DNA, Biosensors, Drug design, DNA-Protein interactions, Enzymatic catalysis.

  • PhD

    Banaras Hindu University

  • - Research Scientist

    Molecular Biophysics Unit, Indian Institute of Science, Bangalore

  • - Guest Scientist

    German Cancer Research Centre, Germany

  • - Postdoc

    National Taiwan Normal University, Taiwan

  • - Postdoc

    Hebrew University of Jerusalem

  • - Lecturer

    Physics Department, Ravenshaw University, Cuttack

  • - Visiting Academic

    University of Queensland, Australia

  • - Member of the IWD Tender Committee

  • - Member of Central Purchase Committee

  • - Warden, Hall-III

  • Senior Research Fellowship Award from the Council of Scientific and Industrial Research

  • International Travel Award from DST

  • Late Shri Harbansh Singh Memorial Best Young Scientist Award by Laser & Spectroscopy Society of India

  • Young Scientist Award from Indian Science Congress

  • Visiting Academic at the University of Queensland, Australia


    School of Chemistry and Molecular Biosciences, University of Queensland, Australia

My courses

Current & Previous

Course Code Course name Category Institute Department Link
Phys-601 Nanobiotechnology PG/PhD Natural Sciences
NS-531 Advanced Quantum Mechanics PG/PhD Natural Sciences
NS-205(g) Modern Physics Natural Sciences
NS-104 Electrodynamics and Optics UG/ Natural Sciences
NS-102 Engineering Mechanics UG/ Natural Sciences
Course Code Course name Category Institute


Areas or Specialisation / Project Activities / Publications / Books

Molecular Biophysics

  • Understanding of DNA Damage and Repair by Enzyme Residues.

    DST-sponsored project. Funds Approved: ~ Rs 14,00000 Tenure: 2009-2012

  • Computational Design of Functional Nucleotides for Artificial Life.

    SERB-sponsored project. Funds approved: Rs 50,00160 Tenure: 2017-2020

  • Mechanisms of Activation of Type I Cytokine Receptors.

    Indian National Science Academy (as a part of Indo-Australia S&T programme), Funds approved: ~Rs 20,00000

  • Mutational properties of DNA base Lesions.

    IIITDM Jabalpur, Funds approved: ~10,00000

  • National Symposium on Innovations in Product Design.

N.R. Jena, Neha Agnihotri, P.C. Mishra (2014) Formation of DNA Lesions, Its Prevention and Repair. Book Title: Computational Techniques in Pharmacy and Medicine, Springer, 59-94.

  • A Few Selected Publications:

    N. R. Jena* & P. Das (2021): Hybrid nucleobases as new and efficient unnatural genetic letters, J. Biomol. Struct. Dyn., DOI: 10.1080/07391102.2021.2003863.

    Suyash Pant, N.R. Jena*, (2021) Inhibition of the RNA-dependent RNA polymerase of SARS-CoV-2 by Short Peptides, Eur. J. Pharm. Sci. 167, 106012.

    N.R. Jena*, (2021) Drug Targets and Therapeutics against SARS-CoV-2, Chemical Physics Impact 2, 100011.

    N.R. Jena*, Suyash Pant, Hemant Kumar Srivastava, (2021) Artificially Expanded Genetic Information Systems as Potent Inhibitors of the RNA-dependent RNA polymerase of SARS-CoV-2. J. Biomol. Struct. Dyn. 1-17, doi: 10.1080/07391102.2021.1883112.

    N.R. Jena, (2020) Role of Different Tautomers on the Base-Pairing Abilities of Some of the Vital Antiviral Drugs used Against COVID-19. Phys. Chem. Chem. Phys., 22, 28115-28122.

    N.R. Jena* (2020) Identification of Potent Drugs and Antiviral Agents for the Treatment of the SARS-CoV-2 Infection. ChemRxiv. Preprint.

    N.R. Jena*, (2020) Electron and Hole Interactions with P, Z, and P:Z and the Formations of Mutagenic Products by Proton Transfer Reactions, Phys. Chem. Chem. Phys. 22, 919-931.

    B. Behera, P. Das, N.R. Jena* (2019) Accurate Base Pair Energies of Artificial Genetic Alphabets: Clues for Their Mutagenic Characteristics. J. Phys. Chem. B 123, 31, 6728-6739.

    N.R. Jena*, (2019) Manganese Coordinated Tyrosine Bio Materials for the Sensing of Reactive Oxygen Species. ChemistrySelect 4, 6945-6953.

    N.R. Jena*, C. Patel, S.C. Sahoo, P.C. Mishra (2018), Cysteine-metal Porous Frameworks as Biosensing Elements for the Adsorption of Reactive Oxygen Species., ChemistrySelect 3, 7732-7740.

    N.R. Jena*, P. Das, B. Behera, P.C. Mishra, (2018) Analogues of P and Z as Efficient Artificially Expanded Genetic Information System., J. Phys. Chem. B., 34, 8134-8145.

    M.K. Tiwari, N.R. Jena, P.C. Mishra (2018), Mechanisms of Scavenging Superoxide, Hydroxyl, Nitrogen Dioxide and Methoxy Radicals by Allicin: Catalytic Role of Superoxide Dismutase in Scavenging Superoxide Radical. J. Chem. Sci., 130, 105.

    N.R. Jena*, P.C. Mishra (2016) Normal and Reverse Base Pairs of Iz and Oz Lesions in DNA: Structural Implications for Mutagenesis, RSC Advances, 6, 64019-64027.

    N.R. Jena*, Manju Bansal, P.C. Mishra (2016) Conformational Stabilities of Iminoallantoin and its Base Pairs in DNA: Implications for Mutagenicity, Physical Chemistry Chemical Physics, 18, 12774-12783.

    N.R. Jena*, V. Gaur, P.C. Mishra (2015) The R-and S-diastereoisomeric Effects on the Guanidinohydantoin-induced Mutations in DNA, Phys. Chem. Chem. Phys. 17, 8111-18120.

    N.R. Jena*, A.E. Mark, P.C. Mishra (2014) Does Tautomerization of FapyG Influence its Mutagenicity? ChemPhysChem, 15, 1779-1784.

    N.R. Jena*, P.C. Mishra (2013) Is FapyG Mutagenic? Evidence from the DFT Study. ChemPhysChem 14, 3263-3270.

    N.R. Jena* (2012) DNA Damage by Reactive Species: Mechanisms, Mutation and Repair. J. Biosci. 37, 503-517.

    N.R. Jena*, P.C. Mishra (2012) Formation of Ring-opened and Rearranged Products of Guanine: Mechanisms and Biological Significance. Free Radic. Biol. Med. 53, 81-94.

    N.R. Jena* (2012) Binding of Bis Like and Other Ligands with the GSK-3? Kinase: A Combined Docking and Molecular Dynamics Study. J. Mol. Model. 18, 631-644.

    N.R. Jena*, Manju Bansal (2011) Mutagenicity Associated with O6-Methylguanine DNA Damage and Mechanism of Nucleotide Flipping by AGT During Repair. Phys. Biol. 8, 046007.

    P.K. Shukla, N.R. Jena, P.C. Mishra (2011) Quantum Theoretical Study of Molecular Mechanisms of Mutation and Cancer: A review. Proc. Natl. Acad. Sc. A (India), 81A, 79-98.

    N.R. Jena*, P.S. Shukla, H.S. Jena, P.C. Mishra, S. Suhai (2009) O6-Methylguanine Repair by O6-Alkylguanine Alkyl Transferase. J. Phys. Chem. B, 113, 16285-16290.

    W.-H. Wang, N.R. Jena, Y.-C. Wang, Y.-C. Sun (2009) A 3D-QSAR study of Celebrex-based PDK1 Inhibitors Using CoMFA Method. J. Chin. Chem. Soc. 56, 59-64.

    N.R. Jena*, P.C. Mishra, S. Suhai (2009) Protection against Radiation-Induced DNA Damage by Amino Acids: A DFT Study. J. Phys. Chem. B 113, 5633-5644.

    N.R. Jena, P.C. Mishra (2009) Interactions of Guanine, Its Anions and Radicals with Lysine in Different Charge States. J. Phys. Chem. B 11, 5418-5424.

    N.R. Jena, P.S. Kushwaha, P.C. Mishra (2008) Reaction of Hypochlorous Acid with Imidazole: Formation of 2-Chloro and 2-Oxoimidazoles. J. Comput. Chem. 29, 98-107.

    N.R. Jena, P.C. Mishra (2007) Formation of 8-Nitroguanine and 8-Oxoguanine Due to Reactions of Peroxynitrite with Guanine. J. Comput. Chem. 28, 1321-1335.

    N.R. Jena, P.C. Mishra (2007) A Theoretical Study of Some New Analogues of the Anti-Cancer Drug Camptothecine. J. Mol. Model. 13, 267-274.

    N.R. Jena, P.C. Mishra (2006) Addition and Hydrogen Abstraction reactions of an OH Radical with 8-oxoguanine. Chem. Phys. Letts. 422, 417-423.

    N.R. Jena, P.C. Mishra (2005) Mechanisms of Formation of 8-oxoguanine Due to Reactions of One and Two OH Radicals and the H2O2 Molecule with Guanine: A Quantum Computational Study. J. Phys. Chem. B 109, 14205-14218.

    N.R. Jena, P.C. Mishra (2005) An ab-initio and Density Functional Study of Microsolvation of Carbon Dioxide in Water Clusters and Formation of Carbonic Acid. Theor. Chem. Accts. 114, 189-199.

    N.R. Jena, P.C. Mishra (2005) Study of Relationship of Atomic Orbital Hybridization with Bonding Using Hybridization Displacement Charge: Optimal Hybridization Principle. J. Mol. Struct. (Theochem) 719, 75-84.

    N.R. Jena, Neha Agnihotri, P.C. Mishra (2014) Formation of DNA Lesions, Its Prevention and Repair. Book Title: Computational Techniques in Pharmacy and Medicine, Springer, 59-94, edited by Leonid Gorb, Victor Kuz'min, Eugene Muratov, ISBN: 978-94-017-9257-8.

    *Corresponding Author

M. Tech./M.Des.

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Ph. D.

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